The VERI reactor series is often a glass-lined steel reactor physique which has a sound borosilicate glass cover. The mixture glass/glass-lined structure was produced within the pharmaceutical sector's demand from customers for maximum purity and optimized heat and mass transfer combined with suitability for GMP use. Our mixture reactor product is widely used in pilot plant units due to its robust style and design.
In case you have any questions and/or problems, make sure you Really don't hesitate to Speak to us for additional facts
For those who have any questions and/or fears, please don't hesitate to Get in touch with us for more information and facts
The interseal dry9000® technology was used for all agitator shaft sealings. Gains these kinds of pretty much as good Production Exercise (GMP) style and design, simplicity of cleaning and sterilization, no need to have for sealing source program, no risk of merchandise decline, as a result of sealing fluid contamination; and no need to have of cleaning or monitoring of supply system were the motorists for The shopper’s conclusion to choose with the verified dry9000 technologies.
Tantalum is actually a typically used repair substance for glass mainly because it has really very similar corrosion resistance. You'll find, on the other hand, a number of exceptions by which tantalum corrodes at a better amount. In these scenarios, the tantalum could embrittle when hydrogen could be the byproduct of a corrosive reaction. By avoiding galvanic couples, you might help discourage this from occurring. Common inspection of all patches and plugs also needs to be done to check for indications of embrittlement (these indications getting missing items or cracks inside the tantalum).
For condensable vapor additions, incorporating a small degree of noncondensible vapor for instance nitrogen to avoid bubble collapse.
Should you be new to glass-lined steel devices, it might be scary when it arrives time to find out the specifications in the vessel. Particularly when filling out our Reactor Specification Type, you could possibly find yourself with a lot more “don’t know�?and “not sure�?responses than actual specs…Which’s ok.
The glass reactor head delivers fantastic visibility for observation of system scale up and development. In addition, it simplifies the inspection approach if you find yourself confirming a CIP course of action. By wanting ideal in the reactor address you can easily evaluate essential aspects of your Procedure, which include if your procedure is foaming, whether the solids disperse or clump, and any mixing concern That may be occurring (e.
A third possibility, which we seek advice from as being the VERI reactor, gives the very best of each worlds. The glass-lined steel body permits larger jacket pressures, permitting for bigger warmth transfer fees by means of larger turbulent jacket flows. The human body’s materials of design also permits better temperature differentials, once again supplying higher warmth transfer. Due to flanged bottom outlet link, the VERI reactor system also can employ the De Dietrich glass-lined steel Cleanse Valve, which allows for a number of features with no must interrupt the method and without the need of dismantling the glass lined reactor wikipedia valve. The glass reactor head offers great visibility for observation of process scale up and growth.
Also, 1 should really check with the manufacturer’s chart of optimum Harmless-temperature differentials and adhere to it strictly. In order to avoid thermal shock due to a runaway exothermic reaction, A fast-reaction temperature sensor could be put in inside a baffle, bottom outlet valve or thermowell to alert the operator of dangerous temperature will increase.
On drilling a hole, prevent the suggestion from the drill from slipping around the glass by turning the chuck by hand and applying pressure, such that the idea cuts its way with the lining.
The harm commonly appears as microscopic holes that go every one of the way down into the steel substrate; chipping may or may not occur. You may as well commonly see a discoloration, or "aura", around the pinhole. Reglassing is necessary to fix electrostatic discharge injury. To prevent Placing your vessel at risk, keep the agitation speeds at a bare minimum and insert materials by means of dip tubes so which they enter underneath the liquid degree line.
It is always advisable that a certified technician performs spark testing in glass-lined equipment. If somebody at your facility has not been qualified on the correct approach for spark testing then a provider expert must be hired to execute the test in your behalf. Once the process is mishandled, it can build pinholes from the glass that could seem similar to electrostatic discharge damage. Spark testing destruction is frequently small enough that A 3-piece plug will protect the problematic region, unless a person produces many pinholes about a big region of your vessel.
In cold climates, Specific safeguards need to be taken to shield glass-lined gear which is used for outside storage or in regions that are not heated. In spots wherever temperatures tumble down below freezing, jackets needs to be drained and plugged to prevent h2o entry.